The Exploratorium allows visitors to examine the world through science, art, and human perception. Its mission is to create inquiry-based experiences that transform learning worldwide. It has been described by the New York Times as the most important science museum to have opened since the mid-20th century, an achievement attributed to "the nature of its exhibits, its wide-ranging influence and its sophisticated teacher training program." 

The campus at Piers 15 & 17 set a net-zero energy goal by utilizing solar, wind and water to operate. The new site contains over 600 exhibits, 25% of which were developed specifically for the Pier 15 site. With the exception of some art installations, all exhibits are developed and made onsite. Indoor and outdoor spaces are divided into six galleries, each highlighting specific content. The rebuild and relocation of gallery exhibits, labs, tinkering studio and shop were managed by Place Partners.